Expert+Page

=__//My Expert, Masato Yamamoto M.D., Ph. D //__=

My expert is Dr. Masato Yamamoto, who has a M.D. and Ph. D. If you didn't know, M.D. stands for Medical degree and Ph. D. stands for doctor of Philosophy. He earned his M.D. from Osaka University School of Medicine in 1988. He then received his Ph.D. from the same Osaka University School of Medicine in 1997. In 1999, he did a postdoctoral fellowship, or transfered in his job with a guaranteed job, to the University of Alabama in Birmingham, or UAB. He remained there for 8 years and joined the Department of Surgery at the University of Minnesota in August 2006. His research interests are in GI-cancer translational research, gene therapy of cancer, and adenoviral vectors. He also has many publications. Many of the things on my wikispaces were said by Dr. Yamamoto.

Dr. Yamamoto has many lab members. They are:

Julia Davydova, M.D., Ph.D. Senior Research Associate / Research Assistant Professor, Department of Surgery Vector construction and preparation. Vector function analyses in vitro and in vivo Immunological approach for pancreatic cancer

Satoshi Yamasaki, M.D., Ph.D. Post-Doctorial Fellow Development of new vector

Yoshiaki Miura, M.D., Ph.D. Post-Doctorial Fellow Development of new vector

Shigenori Hoshino, M.D., Ph.D. Post-Doctorial FellowDevelopment of new therapy for pancreatic cancer

Leonard Armstrong, M.D. Resident, Department of Surgery Immunological approach for pancreatic cancer

Eric J. Brown, B.S. Assistant Scientist Assisting lab member’s experiments

Ms. JooHee Han Under Grad Student Immunological approach for pancreatic cancer



Equpitment in the lab: I asked Dr. Masato what equiptment he has in his lab, and he made a quick list for me. It was a very detailed list, and there were many, many of them. All of them were too complicated and I only recognized a handful of them. Some that I recognized were the thin tissue slicer, the basic translational equpiment, the microscope, the MACS(a cell separation system), and biochemistry core equipments. His lab/facility is 3000 squared feet and has many equpitments for his research.

What they do in the lab: Dr. Yamamoto and his lab members do a number of things, which they divide up to their specialties, listed above. They make new virus vectors, put them into bacteria and reproduce them, test them on basic stem cells(cells that when go through mitosis, their daughter cells can differentiate to other types of cells), and test them on mice. They make viral vectors by using plasmid and enzymes and switching around DNA and mix them gently with a special machine that moves in a circular shape. If you have not yet seen the Virus Vector page, please read it by going to Virus Vector. If the tests on the stem cells and mice are positive, they do many more tests to make sure of their effects. If the effects on the mice are significantly good, they may develop it even more or send it to the FDA to get it tested.

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